Which statins must be taken at bedtime?
To maximize the effects of statins with a short half-life, fluvastatin, lovastatin, and simvastatin should be dosed at bedtime allowing the greatest drug concentration to be present during peak endogenous cholesterol synthesis.
Can Atorvastatin cause sleep problems?
The current evidence, from well-run research trials of more than 100,000 patients, is that statins do not cause insomnia or any other sleep disturbance, compared with a dummy pill (placebo).
What should you not take with atorvastatin?
While taking atorvastatin (Lipitor), avoid high- fat and high-cholesterol foods as part of your overall treatment. You should avoid large quantities of grapefruit or grapefruit juice, which can increase the risk of serious side effects. Also, avoid excess alcohol use, as this may cause serious liver problems.
What are the most common side effects of atorvastatin?
Commonly reported side effects of atorvastatin include: hemorrhagic stroke, arthralgia, diarrhea, and nasopharyngitis. Other side effects include: urinary tract infection, insomnia, limb pain, muscle spasm, musculoskeletal pain, myalgia, and nausea.
Do statins age you faster?
However, it is not the only mechanism that has been shown to be, and which ones are causal has not really been determined. Interestingly, another study recently reported that statins could slow aging, as they were found to be associated with longer telomere length.
Why you should never take statins?
Very rarely, statins can cause life-threatening muscle damage called rhabdomyolysis (rab-doe-my-OL-ih-sis). Rhabdomyolysis can cause severe muscle pain, liver damage, kidney failure and death. The risk of very serious side effects is extremely low, and calculated in a few cases per million people taking statins.
Can Atorvastatin keep you awake at night?
The top-selling statins are atorvastatin ( Lipitor ), lovastatin (Mevacor), rosuvastatin (Crestor) and simvastatin (Zocor). How they can cause insomnia: The most common side effect of all types of statins is muscle pain, which can keep people who take them awake at night and unable to rest.
Does atorvastatin cause weight gain?
When the data was further evaluated, researchers found that 8.1% of the newly-diagnosed diabetics were taking atorvastatin 10 mg; 9.2% of the newly-diagnosed diabetics were taking atorvastatin 80 mg. One year after randomization, both men and women participants had significant weight gain.
What does Atorvastatin do to the body?
Atorvastatin is in a class of medications called HMG-CoA reductase inhibitors ( statins ). It works by slowing the production of cholesterol in the body to decrease the amount of cholesterol that may build up on the walls of the arteries and block blood flow to the heart, brain, and other parts of the body.
Can I eat oranges while taking atorvastatin?
Be mindful that other citrus fruits might also interact with lovastatin, atorvastatin, and simvastatin. The list includes tangelos, pomelos, bitter oranges, and Seville oranges. These foods can also affect how your body metabolizes the medication.
What happens if you forget to take atorvastatin?
If you miss a dose of LIPITOR, take it as soon as you remember. Do not take LIPITOR if it has been more than 12 hours since you missed your last dose. Wait and take the next dose at your regular time. Do not take 2 doses of LIPITOR at the same time.
Can I take atorvastatin every other day?
Conclusions: In hypercholesterolemia patients, atorvastatin 10 mg every other day is safe and effective in lowering TC, TG, with LDL-c and a slight increase in HDL-c.
What are the negative side effects of atorvastatin?
Side effects of atorvastatin include: Gastrointestinal symptoms such as diarrhea. Cold symptoms such as a runny or stuffy nose. Joint pain. Insomnia. Urinary tract infection. Nausea. Loss of appetite. Indigestion symptoms such as stomach discomfort or pain.
What foods should be avoided when taking statins?
Grapefruit and statins: Eating grapefruit, either the fruit itself or as juice, can slow the body’s ability to metabolize statin cholesterol-lowering drugs, which include Lipitor, Crestor and Zocor.
Is depression a side effect of atorvastatin?
Of the individual statins, simvastatin, by far the most widely used agent, was associated with a 7% reduction in the risk of developing depression, whereas atorvastatin was associated with an 11% increase in the risk of developing depression.